{"id":1557,"date":"2026-10-20T10:09:49","date_gmt":"2026-10-20T01:09:49","guid":{"rendered":"http:\/\/tet.brc.riken.jp\/ja\/?page_id=1557"},"modified":"2026-10-20T10:31:08","modified_gmt":"2026-10-20T01:31:08","slug":"home-%e6%9b%b4%e6%96%b02026","status":"publish","type":"page","link":"http:\/\/tet.brc.riken.jp\/ja\/","title":{"rendered":"HOME"},"content":{"rendered":"\n
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GENOME EPIGENOME LIFE<\/p>\n\n\n\n

Decoding
Life through
Genome Regulation<\/h1>\n\n\n\n

We integrate transcriptome and epigenome
to understand how genome regulation
shapes development, cell identity, and disease
across species.<\/p>\n\n\n\n

Our Research \u2192<\/strong><\/p>\n<\/div>\n<\/div><\/div>\n\n\n\n

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Our Research<\/h2>\n\n\n\n

\u79c1\u305f\u3061\u306e\u7814\u7a76<\/p>\n<\/div>\n\n\n\n

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We explore epigenetic regulation and non-coding genome function through innovative technologies to better understand development and disease.<\/p>\n<\/div>\n<\/div>\n\n\n\n

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01<\/p>\n\n\n\n

Function of the Non-coding Genome<\/strong><\/h2>\n\n\n\n

We investigate how non-coding genomic regions, including enhancers, silencers, and insulators, regulate gene expression, cell fate, and organismal phenotypes.<\/p>\n<\/div>\n\n\n\n

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02<\/p>\n\n\n\n

Development and Disease<\/strong><\/h2>\n\n\n\n

We investigate how genetic variation and epigenetic regulation influence cell fate, development, reproduction, and disease using human iPS cells and mouse models.<\/p>\n<\/div>\n\n\n\n

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03<\/p>\n\n\n\n

Single-cell & Multi-omics Technologies<\/strong><\/h2>\n\n\n\n

We develop and apply cutting-edge single-cell and multi-omics technologies to investigate cellular diversity and the underlying mechanisms of epigenetic regulation.<\/p>\n<\/div>\n\n\n\n

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04<\/p>\n\n\n\n

AI for Genome & Cell Regulation<\/strong><\/h2>\n\n\n\n

We develop and apply AI models to integrate multi-omics data, uncover regulatory mechanisms, and predict how genetic variation influences cellular states and disease.<\/p>\n<\/div>\n\n\n\n

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RIKEN BRC's Resources<\/h2>\n\n\n\n

\u7406\u7814BRC\u306e\u30d0\u30a4\u30aa\u30ea\u30bd\u30fc\u30b9<\/p>\n<\/div>\n\n\n\n

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We leverage RIKEN BRC's unique bioresources to investigate genome regulation, development, and disease.<\/p>\n<\/div>\n<\/div>\n\n\n\n

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Mouse Models<\/h2>\n\n\n\n

In vivo functional studies using genetically engineered mouse models.<\/p>\n<\/div>\n\n\n\n

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Human iPS Cells<\/h2>\n\n\n\n

Research using diverse human iPS cell lines derived from healthy individuals and patients with various diseases.<\/p>\n<\/div>\n\n\n\n

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Join us!<\/h2>\n\n\n\n

We welcome motivated students, research staff, and postdocs to join us in exploring epigenetic genome regulation.<\/p>\n\n\n\n

More Details \u2192<\/a><\/strong><\/p>\n<\/div>\n\n\n\n

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Our Research \u79c1\u305f\u3061\u306e\u7814\u7a76 We explore epigenetic regulation and non-coding genome function through innovative technol […]<\/p>\n","protected":false},"author":10,"featured_media":0,"parent":0,"menu_order":0,"comment_status":"closed","ping_status":"closed","template":"","meta":{"_lightning_design_setting":{"layout":"col-one-no-subsection","site_body_padding":"true"},"footnotes":"","_wp_rev_ctl_limit":""},"class_list":["post-1557","page","type-page","status-publish","hentry"],"_links":{"self":[{"href":"http:\/\/tet.brc.riken.jp\/ja\/wp-json\/wp\/v2\/pages\/1557","targetHints":{"allow":["GET"]}}],"collection":[{"href":"http:\/\/tet.brc.riken.jp\/ja\/wp-json\/wp\/v2\/pages"}],"about":[{"href":"http:\/\/tet.brc.riken.jp\/ja\/wp-json\/wp\/v2\/types\/page"}],"author":[{"embeddable":true,"href":"http:\/\/tet.brc.riken.jp\/ja\/wp-json\/wp\/v2\/users\/10"}],"replies":[{"embeddable":true,"href":"http:\/\/tet.brc.riken.jp\/ja\/wp-json\/wp\/v2\/comments?post=1557"}],"version-history":[{"count":10,"href":"http:\/\/tet.brc.riken.jp\/ja\/wp-json\/wp\/v2\/pages\/1557\/revisions"}],"predecessor-version":[{"id":2000,"href":"http:\/\/tet.brc.riken.jp\/ja\/wp-json\/wp\/v2\/pages\/1557\/revisions\/2000"}],"wp:attachment":[{"href":"http:\/\/tet.brc.riken.jp\/ja\/wp-json\/wp\/v2\/media?parent=1557"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}