GENOME EPIGENOME LIFE
Decoding
Life through
Genome Regulation
We integrate transcriptome and epigenome
to understand how genome regulation
shapes development, cell identity, and disease
across species.
Our Research →
Our Research
私たちの研究
We explore epigenetic regulation and non-coding genome function through innovative technologies to better understand development and disease.
01
Function of the Non-coding Genome
We investigate how non-coding genomic regions, including enhancers, silencers, and insulators, regulate gene expression, cell fate, and organismal phenotypes.
02
Development and Disease
We investigate how genetic variation and epigenetic regulation influence cell fate, development, reproduction, and disease using human iPS cells and mouse models.
03
Single-cell & Multi-omics Technologies
We develop and apply cutting-edge single-cell and multi-omics technologies to investigate cellular diversity and the underlying mechanisms of epigenetic regulation.
04
AI for Genome & Cell Regulation
We develop and apply AI models to integrate multi-omics data, uncover regulatory mechanisms, and predict how genetic variation influences cellular states and disease.
RIKEN BRC's Resources
理研BRCのバイオリソース
We leverage RIKEN BRC's unique bioresources to investigate genome regulation, development, and disease.
Mouse Models
In vivo functional studies using genetically engineered mouse models.
Human iPS Cells
Research using diverse human iPS cell lines derived from healthy individuals and patients with various diseases.
Join us!
We welcome motivated students, research staff, and postdocs to join us in exploring epigenetic genome regulation.